IS CARDIOVASCULAR RISK PROFILING FROM UK BIOBANK RETINAL IMAGES USING EXPLICIT DEEP LEARNING ESTIMATES OF TRADITIONAL RISK FACTORS EQUIVALENT TO ACTUAL RISK MEASUREMENTS? A PROSPECTIVE COHORT STUDY DESIGN

Is cardiovascular risk profiling from UK Biobank retinal images using explicit deep learning estimates of traditional risk factors equivalent to actual risk measurements? A prospective cohort study design

Objective Despite extensive exploration of potential biomarkers of cardiovascular diseases (CVDs) derived from retinal images, it remains unclear how retinal images contribute to CVD risk profiling and how the results can inform lifestyle modifications.Therefore, we aimed to determine the performance of cardiovascular risk prediction model from ret

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Adipokinetic Hormone Receptor Mediates Lipid Mobilization to Regulate Starvation Resistance in the Brown Planthopper, Nilaparvata lugens

Lipid storage must be efficiently mobilized to sustain the energy demands during processes of exercise or starvation.In insects, adipokinetic hormone (AKH) and brummer lipase are well-known regulators of lipid mobilization.We recently demonstrated that brummer-dependent lipolysis regulates starvation resistance in the brown planthopper, Nilaparvata

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Study of Baicalin toward COVID-19 Treatment: In silico Target Analysis and in vitro Inhibitory Effects on SARS-CoV-2 Proteases

Negative impacts of COVID-19 on human health and economic and social activities urge scientists to develop effective treatments.Baicalin is a natural flavonoid, extracted from a traditional medicinal plant, previously reported with anti-inflammatory activity.In this study, we used pharmacophore fitting and molecular docking to screen and determine

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Potentially conjugative plasmids harboring Tn6636, a multidrug-resistant and composite mobile element, in Staphylococcus aureus

Objectives: This study aimed to provide detailed genetic characterization of Tn6636, a multidrug-resistant and composite mobile element, in clinical isolates of Staphylococcus aureus.Methods: A total of 112 ermB-positive methicillin-susceptible S.aureus (MSSA) and 224 ermB-positive methicillin-resistant S.aureus (MRSA) isolates collected from 2000

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